Rare case of rilpivirine-induced severe allergic hepatitis

A Case of Severe Hepatitis due to Varicella Zoster

Allergic hepatitis induced by drugs.

PURPOSE OF REVIEW To examine recent advances in our understanding of how drugs can trigger a hypersensitivity reaction in the liver, how tolerance is lost, the mechanisms of damage to hepatocytes and the strategies towards a better assessment of an idiosyncratic drug liver reaction. RECENT FINDINGS Formation and presentation of drug-protein adducts, or a direct interaction with the major hist...

A Rare Case of Hepatitis E Induced Viral Thyroiditis

We report a one of its kind case of a 26-year-old Gentleman, who had initially presented to our hospital with acute symptoms of viral hepatitis. Initial laboratory studies done revealed an elevated liver function test with an elevated Anti-HEV serology and thus the patient was diagnosed and managed for Viral Hepatitis E. The patient had no prior history of any co-morbid conditions but was found...

Clopidogrel-Induced Severe Hepatitis: A Case Report and Literature Review

Clopidogrel is a commonly prescribed antiplatelet agent that carries a rare risk of hepatotoxicity. We describe a case of severe clopidogrel-induced hepatitis with liver biopsy assessment. Prompt recognition and withdrawal of the offending agent are imperative to prevent progression and potentially fatal liver injury.

Nafcillin-Induced Allergic Eosinophilic Cholestatic Hepatitis

A 71-year-old female with no history of liver disease or antibiotic allergy developed jaundice with elevated liver enzymes and eosinophilia following treatment with nafcillin for septic arthritis. Further workup demonstrated hepatocellular dysfunction and liver biopsy showed expansion of portal tracts by lymphocytes and eosinophils consistent with a hypersensitivity reaction. Nafcillin and rela...